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IGF-1 LR3 is a long-arginine analog of insulin-like growth factor 1, engineered with a substituted arginine residue at position 3 and a 13-amino acid extension on the N-terminus that resists binding to IGF binding proteins found in serum

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IGFBP-3 (Insulin-like Growth Factor Binding Protein-3) is the main transport protein for IGF-1 in the bloodstream