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Some users experience nausea, indigestion, bloating, or stomach discomfort, particularly when taking pills on an empty stomach

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Understanding steady state also helps explain why microdosing protocols work differently than standard escalation

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Animal experiments have shown that the medicine slows down the build-up of proteins in the cerebral cortex

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The SURMOUNT-1 trial showed that while average weight loss at 72 weeks reached 1521% depending on dose, the trajectory was not linear, with many participants experiencing temporary plateaus

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doi: 10.3390/ijms17091534 201 ZuoY

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