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For Arbutin_d, the key interacting residues are S356, E326, and E184 (Table 2)

In mesothelioma models, SFN disrupts PRMT5/MEP50 complex function, inhibiting its methyltransferase activity, reactivating tumor suppressor expression, and suppressing cancer cell proliferation, invasion, and stem-like properties (79, 80)

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It is perfect in giving a glow to the skin by minimizing and prevent age spots and other forms of dis-colouration common in aging skin

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