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Concerns If GLP-1s Can Deliver on Treating Fibrosis If we can clear up the fat in patients with early-stage disease with an effective therapy for underlying obesity and diabetes before there is any liver scarring, then GLP-1 use is a good thing
A consensus statement from the Growth Hormone Research Society acknowledges that "preclinical data suggest that GH/IGF-I is involved in cancer development." Angiogenesis Concerns: The VEGF/VEGFR2 pathways activated by BPC-157 and other peptides are "active in roughly half of human cancers." While promoting blood vessel formation is beneficial for healing, it's concerning in the context of potential tumor growth
The downstream transcription factors, the IGF-1 receptor cycling, the metabolic switching between anabolism and lipolysis
Ann NY Acad Sci 1963
The best option depends on several factors, including health history, metabolic health, medication tolerance, side effect response, and long-term weight loss goals
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