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Because of the dark red color of hydroxocobalamin, the two most frequently occurring adverse reactions were chromaturia (red-colored urine) which was reported in all subjects receiving a 5 g dose or greater

Animal data in rodent models, the literature describes lifespan extension and reduced tumor incidence in cancer-prone strains

difficulty identifying or characterizing the correct active pharmaceutical ingredient

If a journal publishes a correction or a retraction, Reich notes, academics whose work is called into question may sue (or threaten to do so) over the hit to their reputation, whereas whistleblowers who flag an error are unlikely to sue journals for taking no action