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GLP-1 receptor activation reduces antral motility, alters pyloric function, slows gastric transit, and contributes to nausea, early satiety, bloating, and postprandial fullness in susceptible patients

Within that LBM reduction, liver mass dropped approximately 20% while skeletal muscle showed only modest, often non-significant changes

Disruptions or impairments in mitochondrial network connectivity can lead to detrimental effects on cellular physiology and contribute to the pathogenesis of T21

Clinical trials indicate an average weight loss between 12% and 17%, with certain participants noting a reduction in body weight as high as 21%