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If youve been considering weight loss medications, youve probably come across terms like liraglutide, semaglutide , and GLP-1
1 Contraindications or require Caution: individuals who are pregnant or breastfeeding, have a history of cancer, or have pre-existing liver or kidney conditions
Tirzepatide is formulated to mimic the function of native GIP at the GIPR while also interacting with the GLP1R in a manner different from native GLP1
The consequences of these maladaptive changes are increase in myocardial stiffness and reduced ventricular compliance which play a vital role in the development of LV diastolic dysfunction leading to heart failure with preserved ejection fraction (HFpEF), the most common form of HF in T2DM (40)
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