Yang Y, Du L, Hosokawa M, Miyashita K (2020) Spirulina lipids alleviate oxidative stress and inflammation in mice fed a high-fat and high-sucrose diet
Critical Safety Gaps for Mental Health Applications Unknown effects on cognitive function, memory, personality, mood stability beyond intended therapeutic effect Long-term impacts on brain chemistry (chronic administration effects unexplored beyond 6 weeks in animals) Potential for psychological dependence or tolerance (not studied systematically) Impacts on developing brains in adolescents and young adults (completely unknown with no pediatric studies) Drug Interactions Pose Serious Concerns BPC-157s simultaneous effects on serotonin, dopamine, GABA, glutamate, and nitric oxide systems create multiple theoretical interaction points with psychiatric medications, yet interactions are not well studied. Specific concerns include: With SSRIs and SNRIs: Risk of serotonin syndrome is genuine
ZhengJPWenFQBaiCXWanHYKangJChenPet alPANTHEON study group
(8) Furthermore, it may potentially prevent protein glycation
GM1 was also found to improve patient-reported neuropathy symptoms, but not objective measures of neuropathy severity, in a trial involving colorectal cancer patients (Wang 2020)