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Important safety considerations include contraindications in patients with personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2, caution in those with a history of pancreatitis, increased risk of gallbladder disease, potential for acute kidney injury with dehydration, and possible worsening of diabetic retinopathy with rapid glycemic improvement
Injection-site reactions Redness, mild swelling, itching, or bruising at the injection site are common and typically resolve within 24 to 48 hours
Schedule: 5 days on, 2 days off
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Major drug Interactions: Scopolamine should be used with care in patients taking other drugs that are capable of causing CNS effects such as sedatives, tranquilizers, or alcohol
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