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387:224557 doi: 10.1056/NEJMoa2208601 15 EMA
They interfere with testosterone production, impair sperm quality, and even disrupt hormone signaling in the brain (through the hypothalamic-pituitary-gonadal axis)
Nawrot, J
Gallbladder problems and gallstones are rarer but more serious complications to be aware of, especially in people losing weight rapidly or those with insulin resistance, high cholesterol or other metabolic conditions
My tirzepatide was clear when I got it but now looks yellow A gradual shift from clear to slightly yellow over the use period can be normal, especially for compounded formulations
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