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4.6 Metabolism Plasma, bile, urine, and fecal samples of intact SD rats or BDC rats after a single administration of [3H]BPC157 were analyzed by HPLC combined with a low-energy radionuclide detection technique to obtain the radiometabolite profiles of [3H]BPC157
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the doses were escalated every 4 weeks starting from 0.25 mg to 0.5 mg, 1.0 mg, and 1.7 mg until a dose of 2.4 mg was met and maintained for the remaining 16 weeks
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