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Moreover, they are resistant to DPP-4 activity and have a longer half-life than native GLP-1

Fitch expressed optimism about the study's results

3 Metabolic outcomes of GLP-1RAs in PCOS: from evidence synthesis to Bayesian probability integration The interpretation of clinical evidence presented below follows the core tension between metabolic risk fertility window, as illustrated in Figure 1A: achieving metabolic optimization within a finite reproductive window while strictly adhering to discontinuation and washout protocols to mitigate periconception exposure risks

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These include: Nausea and vomiting (very common, affecting more than 1 in 10 patients) Diarrhoea or constipation Abdominal discomfort or bloating Reduced appetite These symptoms often diminish over several weeks as the body adjusts to the medication