That hormone slows the rate your stomach empties, increases the feeling of fullness, and reduces the appetite signals coming from the brain
Therefore, they cannot define long-term safety, cancer risk, reproductive effects, cardiovascular risk, or a general therapeutic role
A biomarker effect without a clinical one, as seen in EVOKE, is exactly the dissociation that should make researchers cautious about surrogate measures
Common concerns include gastrointestinal symptoms (nausea in 30-50% of patients), injection site reactions, and potential for acute pancreatitis
This process is vital for effective fat burning, especially during exercise or calorie-restricted diets, supporting both weight management and reduced fatigue