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The phagocytic capacity of macrophages toward ferroptotic tumor cells demonstrates anti-tumor activity, with various immune-stimulatory signals released by ferroptotic tumor cells enhancing phagocytic efficiency ( 6 Iron metabolisms influence on macrophage polarization Macrophages store iron through FT binding, with iron-related gene expression profiles varying across polarization stages

Cells expressing APEX2-GFP were enriched by fluorescence-activated cell sorting (FACS), and cells expressing mito-APEX2 were enriched by puromycin selection

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