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Apigenin increased production of cleaved caspase-3, cleaved caspase-8, and cleaved PARP, which inhibited the proliferation and colony formation of HER2+ BT-474 cells (160)

The fat cell targeting mechanism remains active, but with less total adipose tissue available to mobilize, changes occur more gradually

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First, the acceleration of early improvement is clinically meaningful for patients with time-sensitive goals