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Exercise can promote autophagy by activating adenosine monophosphate activated protein kinase (AMPK) / peroxisome proliferator-activated receptor coactivator-1a-1a (PGC-1a) pathway, thus improving the insulin sensitivity of skeletal muscle damage in HFD mice

This gene-environment interaction not only provides new insights for depression prevention and intervention but also forms the basis for developing personalized treatment strategies

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Reductions in liver fat content were generally numerically larger among animals treated with Viking compounds relative to liver fat reductions observed among tirzepatide-treated animals