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Glutathione is an essential cofactor for a number of enzymes, including formaldehyde dehydrogenase, glyoxylase, maleylacetoacetate isomerase, dehydrochlorinase, and prostaglandin endoperoxidase isomerase
& Stamato, T
The interplay of NAD + /NADP + metabolism with circadian clock is further evidenced by the oscillating redox, in which ROS levels display a different liver pattern compared to other tissues due to the unique NAD + oscillation in response to the autonomous hepatic clock
& Uberti, D
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