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Pre-clinical research has reported an increase in VEGF and its receptor VEGFR2, and enhanced migration of endothelial cells
Semaglutide was associated with gastrointestinal adverse events (nausea, vomiting, diarrhea, constipation) which were of mild to moderate severity, short duration, and resolved without treatment discontinuation ( Notably, a recent systematic review showed that compared to other semaglutide doses and GLP-1 RAs, 2.4 mg semaglutide had the greatest effect on weight reduction, controlling glucose level, and reducing BP
Duffy DM
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