semaglutide and bv GLP-1 RAs linked to broad menstrual adverse event signals in reproductive-aged patients Can Semaglutide Cause irregular Periods

Gabrielle Lyon, a board-certified family physician and founder of Muscle-Centric Medicine, has warned that GLP-1 medications can accelerate muscle loss at a rate that would normally take decades compressing years of sarcopenia into weeks

They have not undergone clinical trials for safety and efficacy

think Wall Street Journal reported on that back in January

Wegovy delays gastric emptying and may impact the absorption of oral medications

Even more striking was a separate large analysis, also presented at ACR Convergence 2025 by researchers at Jefferson Health-Einstein in Philadelphia, which used a nationwide database of more than 4,000 psoriatic arthritis patients on GLP-1 medications compared with over 86,000 who werent