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Erythrocyte pathology clearly indicates microcirculatory problems [208, 230, 232, 375], supporting the hypothesis that inadequate microcirculation in Long COVID, leading to ischemia-reperfusion injury, could play a critical role [352]

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IGF-1 LR3 also interacts with other growth-related hormones, such as growth hormone (GH), amplifying the anabolic effects and supporting systemic regeneration