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Sputum cultures revealed Staphylococcus aureus, indicating infection of the chest wall mass and worsening pulmonary infection

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In some experiments, we introduced blockers to the wells after loading with Fluo-4 AM and waited for 15 min before taking readings

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It competitively binds p53, displacing endogenous FOXO4 in senescent cells (Baar et al., 2017) 24-72 hours: Freed p53 translocates to mitochondria in senescent cells, triggering the intrinsic apoptotic cascade