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Inefficient metabolism has been shown to lead to the accumulation of metabolic intermediates that can interfere with mitochondrial function and impair the ability to produce ATP
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Caloric intake was determined from food consumption data (Considering energy density of SD and HFD), and energy balance was calculated as the difference between energy intake and total energy expenditure
Lastly, the $700 billion in market capitalization gains by Novo Nordisk and Eli Lilly since the launch of GLP-1 therapies is a stark indicator of financialization, as these valuations far exceed the cumulative revenue generated by the drugs themselves
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