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Clinical trials demonstrate: Weeks 14 : Minimal weight loss as your body adjusts Months 23 : More noticeable weight reduction as dose escalation continues Months 46 : Steady, consistent weight loss Peak effect : Maximum weight loss typically occurs at 6068 weeks of continuous treatment [15] According to FDA-approved labeling, patients on Wegovy (2.4 mg weekly) lost an average of 15% of their body weight over 68 weeks in clinical trials (STEP 1)

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Most patients begin noticing weight loss within the first four to eight weeks of starting tirzepatide dosing for weight loss in units

Both injectable options come with a choice of additives beyond B12