Course Highlights Discover how combining lifestyle modifications with GLP-1 receptor agonists can improve weight loss, glycemic control, and overall cardiometabolic health Examine the science behind GLP-1 receptor agonists, from their effects on insulin secretion and appetite regulation to next-generation agents like tirzepatide and orforglipron Learn best practices for patient education, dosing strategies, and interprofessional collaboration while addressing contraindications, adverse effects, and compounding warnings Introduction Obesity is a chronic and prevalent condition that impacts health, contributing to higher rates of morbidity and mortality
Mentlein R (2009) Mechanisms underlying the rapid degradation and elimination of the incretin hormones GLP-1 and GIP
Its Danish rival Novo Nordisk is working on 14 leads, including additional studies on the already approved products
Whats changing is the margin for error - and the number of people affected when that margin is exceeded
With respect to VHE, Verrotti and coworkers [69] demonstrated an increase in glutamine production in astrocytes whereas glutamine release was inhibited