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PMCID: PMC5809702

By age 60, that number drops to approximately 80 nanograms per milliliter

Multiple serum biomarkers have been described as potential indicators, not only to identify hepatocyte injury and necrosis but also to help predict patient outcomes based on presence or absence of certain intracellular or intramitochondrial markers

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Taken together, these results suggest that CPP-CAND inhibited the FOXO4-p53 interaction in the nucleus, which enabled the extranuclear transport of p53 and selectively induced apoptosis in senescent cells