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it requires an empty stomach and reaches peak levels 60 to 90 minutes after ingestion
Front-load protein if appetite fades later in the day
For a detailed comparison of all fat-loss peptide options, see our best peptides for weight loss comprehensive guide
Semaglutide activates only GLP-1 receptors (not GIP), which produces slightly less dramatic weight loss on average but may come with fewer side effects for certain individuals
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