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Experimental design considerations include the importance of timing senolytic administration relative to senescence induction or disease progression, as the biological context affects both efficacy and interpretation of results

(PubMed) Magoulas PL, El-Hattab AW

Spending on GLP-1 drugs for currently covered uses under Medicare and Medicaid has increased substantially in a relatively short period of time and could increase further with expanded coverage of GLP-1s for obesity, even at the lower net prices for these medications under both demonstrations

Some Akkermansia strains exhibit antibiotic resistance, which raises theoretical concerns about gene transfer in clinical settings

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