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doi: 10.1111/j.1365-2249.2011.04456.x 45 GarmanLPelikanRCRasmussenALareauCASavoyKADeshmukhUSet al

(15) quantitated -tocopherol absorption in healthy women using two different forms of deuterium-labelled -tocopherol

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[6] Caution is advised in patients with advanced renal impairment or those receiving dialysis, given the renal clearance of carnitine and the risk of accumulation

While formal clinical trials of this specific combination await development, the theoretical basis for synergy is compelling, supported by successful precedents like CagriSema and the impressive individual performance of both compounds