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1h), without influencing GIP levels (Fig
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Since leptin reduces sweet taste sensitivity, diminished leptin signaling in the CNS may contribute to the reduced sweet taste sensitivity observed in individuals with obesity (127)
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[16], who demonstrated that treatment of hASC with 100 nM Ex-4 led to a significant reduction in Hoechst-positive cells, reduced DNA fragmentation, and fewer cells entering early stages of apoptosis
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