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154 The same researchers conducted a four-month crossover trial with 20 perimenopausal women (each participant receiving two months of maca, at a dose of 1 gram twice daily, and two months of placebo, in random order) and found menopausal symptoms, such as hot flashes, night sweats, sleep problems, nervousness, depression, and heart palpitations, and improved parameters of metabolism were reduced during maca treatment
doi: 10.1016/j.nbd.2012.06.024 93
Oxford University Press, New York 1999 Sies, H
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Subsequently, 2.0 mg/kg body weight of caffeine was administered as a 100 ml solution to ensure that the participants could tolerate the bitter taste of caffeine
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