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In order to ensure data quality, cases were removed if they failed two or more quality checks: (1) attention check questions in the online version of the questionnaire, (2) had over 30% item non-response, or (3) had a length less than one quarter of the mean length by mode
Significantly decreased insulin and insulin receptor expression was observed in postmortem AD brain tissue, and changes in downstream insulin signaling molecules, including decreased levels of IRS-1/2, PI3K, p-Akt (51, 54)
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