1 H NMR (400 MHz, CDCl 3 ) 8.94 (t, J = 5.3 Hz, 2H, NH 2), 7.887.62 (m, 30H, ArH 30), 3.843.67 (m, 8H, H 2 -1 2 and H 2 -6 2), 3.07 (dd, J = 11.7, 5.8 Hz, 4H, H 2 -2 2), 1.871.76 (m, 4H, H 2 -4 2), 1.711.49 (m, 8H, H 2 -3 2 and H 2 -5 2)
If the cause of ED shifts over time, the same dose may not match the problem anymore
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