When to Seek Urgent or Emergency Care Stop the infusion and seek urgent medical evaluation for: Trouble breathing, wheezing, throat tightness, facial or tongue swelling, widespread hives, or fainting Persistent chest pain or pressure, severe shortness of breath, irregular heartbeat, or loss of consciousness Severe chills, shaking, high fever, confusion, very low blood pressure, or concern for contaminated product or bloodstream infection Sudden weakness, speech difficulty, severe headache, seizure, or another acute neurologic symptom Severe IV-site pain, rapidly increasing swelling, pale or cool skin, blistering, or loss of sensation A symptom occurring during an infusion should not automatically be labeled a detox reaction. That phrase can delay recognition of allergy, endotoxin exposure, infection, excessive infusion rate, cardiac symptoms, anxiety, or another medical problem

For patients without neurological involvement , hydroxocobalamin 1 mg is administered intramuscularly three times a week for 2 weeks, followed by maintenance injections every three months for life (if due to pernicious anaemia or other non-dietary cause)
Patient Benefits Improves healing Reduces wrinkles and fine lines Heals nerves GHK-CU GHK-Cu is a naturally occurring copper peptide which is naturally produced in many tissues in the body
Int J Nanomedicine
One study involving 20 healthy subjects showed that mecobalamin treatment for 14 days reduced sleep duration [21]