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(1) S Sayeed Ahmad, K Ahmad, E Ju Lee, Y-H Lee, and I Choi (2020) Implications of Insulin-Like Growth Factor-1 in Skeletal Muscle and Various Diseases Cells, 2020 Jul 24, Volume 9 (Issue 8), Page 1773

Recently, treatment with tirzepatide was superior to treatment with semaglutide with respect to reduction in body weight and waist circumference at week 72 among participants with obesity but without diabetes in SURMOUNT-5 trial [26]

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This review highlights key clinical considerations across reproductive stages, emphasizes the primacy of human exposure data where available, and identifies critical evidence gaps requiring future prospective study

Some patients use it as a long-term tool, while others transition off once theyve reached a healthy weight and established lifestyle changes