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Nature (2000) 407(6801):24957

Carotid intimamedia thickness, which provides a measure of cardiovascular disease progression, showed a clear regression, and pioglitazone-treated study participants had fewer incidents of heart attack, stroke and death

The precise connection linking GLP-1 RAs to NA-AION is unclear though some have postulated volume depletion, hypotension, transient microvascular dysregulation, and impaired vascular autoregulation as potential mechanisms

The monoclonal has already undergone a Phase 1 safety trial

You get the full dose every time, with no guessing about how much your body actually used