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Author contributions Daphne Bot: acquisition of data, analysis and interpretation of data, and drafting of the manuscript

The phase 2 dose-ranging trial (NCT02970942) included 320 individuals with histologically proven MASH and hepatic fibrosis F1-F3, randomizing them 3:3:3:1:1:1 to daily subcutaneous administration of semaglutide 0.1, 0.2, or 0.4 mg, or placebo for 72 weeks [18]

MYB The ranscriptional activator Myb (MYB) is a cellular progenitor of the v-Myb oncogene and encode an oncogenic transcription factor that regulates various cellular functions by controlling the expression of a wide array of genes [135]

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