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However, dermatologists often recommend combining IV therapy with targeted treatments like chemical peels or laser toning for best results

Oxidative stress can also upregulate the expression of efflux pump-associated genes, enhance the removal of ROS-damaged molecules and ultimately reduce oxidative damage (Grant and Hung 2013)

Peer review Peer review information Nature Metabolism thanks Florian Greten, Luisa Iommarini and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

Methodology The GoodRx survey was run through YouGov from August through October 2025

These observations are worth taking seriously as a potential therapeutic signal