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According to the review, [GLP-1 receptor] signaling in astrocytes regulates both central and peripheral metabolism, extending from energy balance to neuroplasticity. This signaling also enhances neuron growth, and an increase in astrocytes also increases neuron survival
It also has mild anti-inflammatory effects and may improve blood lipid profiles in some people
More research is needed to verify the effects genetic variations can have on weight loss with GLP-1s
Heres a more in-depth breakdown of how the Mediterranean diet can pair with semaglutide use
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