Docimo Jr, S., Shah, J., Warren, G., Ganam, S., Sujka, J., & DuCoin, C
Clinical translation requires human CSF pharmacokinetic assays to prove BBB bypass, a rigorous dose-escalation Phase I trial to establish a safe human NOAEL for chronic dosing, and an RCT utilizing precise neurocognitive testing (e.g., MoCA) to confirm that murine transcriptomic shifts yield functional neuroprotection in humans
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It is used in research for healing, tissue repair, and inflammation reduction