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Supports fat and protein metabolism
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This two-step engagement is why truncating the N-terminus abolishes activation while leaving binding partly intact, and it is why the position-8 modification can block a protease without destroying agonism: the residue is inside the activating segment but is tolerant of substitution
Subsequently, the sections were deparaffinized through a graded series of ethanol (100%, 70%, 30%) and finally rinsed in PBS, each step lasting 5 min
(2021) GLP-1 receptor agonists: an updated review of head-to-head clinical studies
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