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These products are being promoted to assist with weight loss

Possible Orlistat side effects include gas, increased bowel movements, and fecal incontinence

and Akkermansia spp., effectively moderating the microbial imbalance and colonic inflammation triggered by experimental colitis, alongside preserving the integrity of the mucus barrier (Ke et al., 2021

Yet, these are the very populations now being considered for treatment

Conclusions from research studies published to date are limited due to small sample sizes, lack of randomization in some studies, and a need for more precise tests of thiamin nutritional status