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The most common adverse reactions of exenatide are nausea and vomiting

There are actually two different types: internal and external hemorrhoids

Redness, dryness, or itching at the application site, usually mild and transient

423 It was observed that the GLP-1RA, exendin-4, significantly reduced the TNF- levels caused by various TLR agonists, indicating that exendin-4 can lower the TNF- levels induced by multiple TLR agonists

While cardiovascular death alone didn't reach statistical significance (middle-left panel), consistent directional benefits appeared across heart failure outcomes and all-cause mortality, suggesting broad cardiovascular protection