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Well-designed randomized clinical studies are needed to systematically evaluate the evidence for the use of these hepatoprotective agents as treatment options for APAP-induced liver injury, to determine the timing of initiation of the therapy, and to further define the optimal treatment regimen

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Cysteine is catabolized by several desulfuration reactions that release sulfur in a reduced oxidation state, generating sulfane sulfur or hydrogen sulfide (H 2 S), which can be further oxidized to sulfate

This leads to oxidative stress, which damages healthy cells ( Oxidative stress has been linked to chronic conditions like heart disease, Alzheimers, and cancer, as well as premature aging and the risk of stroke ( Antioxidants like selenium help reduce oxidative stress by keeping free radical numbers in check ( They work by neutralizing excess free radicals and protecting cells from damage caused by oxidative stress