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NF-B was found to be hyperactivated during aging, which impairs the generation of induced pluripotent stem cells, as there is a repression of NF-B during the reprogramming process of stem cells towards a pluripotent state [117]

Psychiatric symptoms, such as paranoia, anxiety, and psychosis, further correlate with the observed abnormalities in the limbic and orbitofrontal regions (Zweben et al., 2004)

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This makes it good for injury modeling, recovery timing studies, and tissue resilience testing

For musculoskeletal injuries, this might include range of motion testing, strength assessments, or imaging follow-up