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Here, we reported an oligopeptide hydrogel that encapsulates cell-penetrating-peptide (CPP)-decorated curcumin-loaded nanoemulsions (Cur-CNEs) to enhance the skin penetration of curcumin for topical treatment of psoriasis

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including IL-6, IL-10, IL-12, IL-17, IL-21, IL-23 [184,185,186]), tumor necrosis factor-alpha, and B-lymphocyte activating factor

Zakowski JJ et al

The appetite effect is a matter of neural signaling: area postrema neurons project to the parabrachial nucleus and onward to forebrain regions that govern the decision to stop eating, and this circuit also engages hedonic pathways that reduce the rewarding value of food