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Since the body cannot produce Vitamin B12 naturally, it must be obtained through diet or supplements

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The CYP4A1 and 4A2 gene expression have been reported to increase with NSAIDs 72,73,74

It is notable that even if the pathway is absent, ascorbate is present in some of these compartments, albeit in more oxidised form (Conklin et al

2024;10(6):e27678