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Alharthi WA et al

Power outage A refrigerator maintains safe temperatures for approximately 4 hours during a power outage if the door remains closed

The Endocrine Society's 2018 clinical practice guideline on testosterone therapy states: "We recommend testosterone therapy for men with symptomatic androgen deficiency to induce and maintain secondary sex characteristics and to improve their quality of life." [2] That guideline informs the diagnostic thresholds used by the platforms above, typically a total testosterone below 300 ng/dL on two fasting morning draws

Qualifying Comorbidities FDA labeling and clinical guidelines commonly recognize: Hypertension (blood pressure 130/80 or taking antihypertensive medication) Type 2 diabetes (HbA1c 6.5% or on glucose-lowering medication) Prediabetes (HbA1c 5.7-6.4% or impaired fasting glucose) Dyslipidemia (elevated LDL, low HDL, or elevated triglycerides) Obstructive sleep apnea (diagnosed via sleep study) Cardiovascular disease (prior MI, stroke, coronary artery disease) Non-alcoholic fatty liver disease / MASLD Polycystic ovary syndrome (PCOS) with metabolic features Osteoarthritis weight-bearing joints Insurance formularies may be stricter some require objective documentation (lab values, sleep study reports) rather than self-report

Cardiovasc Diabetol (2021) 20(1):225