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Participants were randomly assigned to receive a 50 mg dose of Rozebalamin or a placebo, administered via twice-weekly injections into the muscles, for 16 weeks

Nature 649 , 487495 (2026)

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Taken together, these results indicate that OsDHAR has potent chaperone-like properties and is capable of protecting proteins from precipitation and heat-induced loss of enzymatic activity, suggesting that OsDHAR is a potent inhibitor of stress-induced protein aggregation

Zhang, V.X., Sze, K.M-F., Chan, L-K., Ho, D.W-H., Tsui, Y-M., Chiu, Y-T., Husain, A., Huang, H., Tian, L., Wong, C.C-L., Ng, I.O-L