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In July 2024, the FDA issued an alert that warned of the risks of dosing errors in compounded semaglutide products after receiving reports of patients self-administering GLP-1s at dosages five to 20 times higher than prescribed
Best sources of fats to help release GLP-1s: Olive oil (a staple of the Mediterranean diet) Avocados Fatty fish (salmon, sardines, mackerel, arctic char, trout) Nuts and seeds (raw almonds, walnuts, pistachios, whole peanuts, flaxseeds, natural peanut butter, flax seeds, chia seeds, hemp hearts) In fact, a diet high in olive oil increased GLP-1 levels, improved insulin sensitivity, and reduced weight gain in several studies (Bonaruc et al, 2016)
Many people notice these side effects lessen as time goes on with proper support
2025;34(2):e70110
The company argued that an injunction wouldnt protect patients because they would likely be harmed if the court were to enjoin FDAs shortage decision and greenlight further compounding. The evidence submitted to the FDA to prove that the shortage remains also wasnt sufficient, Novo argued, pointing to patient reports from online reporting systems without any meaningful data integrity controls and screenshots purporting to show unavailability of approved drugs. In any event, FDA rightly concluded that localized supply disruptions may exist even when there is not a nationwide drug shortage, Novo wrote
