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Mice acclimatized to the cages for 3 days prior to measurements

But the results of a recent clinical trial suggest it's not as simple as that

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The mouse model used for these experiments is a general knockout and we can therefore discount the possibility that GLP-1 exerts its inhibitory action by paracrine effects secondary to activation of GLP-1Rs in delta and beta cells, suggesting that GLP-1s glucagonostatic effect involves a receptor distinct from GLP-1R